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May reduce cell damage from free radicals

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Specifically, methylene tetrahydrofolate (THF) dehydrogenases catalyze the oxidation of 5,10-methylene-THF to form 10-formyl-THF, which is subsequently oxidized to CO 2 with concomitant NADPH production by 10-formyl-THF dehydrogenases (55)

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One review of the two drugs modestly favored romiplostim over eltrombopag (Cooper 2012)

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